Hepatic granuloma in polymyalgia rheumatica.

Area of Science:

• Hepatology
• Rheumatology
• Internal Medicine

Background:

• Polymyalgia rheumatica is a systemic inflammatory condition.
• Hepatic granuloma is a rare manifestation in polymyalgia rheumatica.
• Liver enzyme abnormalities can occur in polymyalgia rheumatica.

Observation:

• A 62-year-old woman presented with polymyalgia rheumatica.
• Elevated hepatic enzymes and liver granuloma were observed.
• The patient showed symptoms consistent with polymyalgia rheumatica and liver involvement.

Findings:

• Low-dose corticosteroids led to significant clinical improvement.
• Liver function tests normalized following corticosteroid treatment.
• This case represents the first reported instance of polymyalgia rheumatica with liver granuloma in Israel.

Implications:

• Corticosteroids may be effective in managing polymyalgia rheumatica with hepatic granuloma.
• This finding expands the understanding of polymyalgia rheumatica's extra-articular manifestations.
• Highlights the importance of considering liver involvement in polymyalgia rheumatica patients with abnormal liver tests.