Length-dependent changes of pacemaker frequency in the isolated rabbit sinoatrial node

Related Experiment Video

Updated: Oct 21, 2026

Methods for the Isolation, Culture, and Functional Characterization of Sinoatrial Node Myocytes from Adult Mice
09:32

Methods for the Isolation, Culture, and Functional Characterization of Sinoatrial Node Myocytes from Adult Mice

Published on: October 23, 2016

A Kamiyama, I Niimura, H Sugi

    The Japanese Journal of Physiology
    |January 1, 1984
    PubMed

    Keywords:
    sinoatrial nodeheart rate regulationmechanical deformationcardiac electrophysiology

    More Related Videos

    Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice09:20

    Microelectrode Array Recording of Sinoatrial Node Firing Rate to Identify Intrinsic Cardiac Pacemaking Defects in Mice

    Published on: July 5, 2021

    Translational Rabbit Model of Chronic Cardiac Pacing06:14

    Translational Rabbit Model of Chronic Cardiac Pacing

    Published on: January 6, 2023

    Related Concept Videos

    Electrophysiology of Normal Cardiac Rhythm01:19

    Electrophysiology of Normal Cardiac Rhythm

    The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase of...
    Conduction System of the Heart01:19

    Conduction System of the Heart

    Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
    The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
    Conduction System of the Heart01:20

    Conduction System of the Heart

    The cardiac conduction system produces and transmits electrical impulses that prompt myocardial contraction, ensuring efficient heart function. This intricate system ensures that the heart beats in a coordinated and efficient manner, beginning with the atria and then the ventricles. The conduction system optimizes cardiac output by maintaining this precise sequence, which is crucial for adequate blood circulation.
    This system relies on the unique properties of nodal and Purkinje cells:...
    Cardiac Action Potential01:30

    Cardiac Action Potential

    Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
    The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
    Ionic Basis of Cardiac Action Potentials
    Dysrhythmias III: Characteristics of Dysrhythmias01:29

    Dysrhythmias III: Characteristics of Dysrhythmias

    Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per minute.
    Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

    Dysrhythmias IV: Characteristics of Bradyarrhythmias

    Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...