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Related Experiment Videos

The Mallory-Weiss lesion: a five-year experience.

P Kerlin, D Bassett, A K Grant

    The Medical Journal of Australia
    |May 6, 1978
    PubMed
    Summary

    The Mallory-Weiss lesion is a common cause of upper gastrointestinal bleeding, often linked to vomiting and alcohol. While usually benign, it can be serious when combined with other health issues.

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    Area of Science:

    • Gastroenterology
    • Internal Medicine

    Background:

    • The Mallory-Weiss lesion is a tear at the gastroesophageal junction.
    • It is a recognized cause of upper gastrointestinal bleeding.

    Purpose of the Study:

    • To investigate the incidence and characteristics of Mallory-Weiss lesions.
    • To understand the clinical presentation and outcomes of patients with this condition.

    Main Methods:

    • Retrospective survey of patients with upper gastrointestinal bleeding between 1972 and 1976.
    • Endoscopic diagnosis of Mallory-Weiss lesions.
    • Analysis of patient demographics, history, lesion location, treatment, and outcomes.

    Main Results:

    • Mallory-Weiss lesions were diagnosed in 7.7% of patients with upper gastrointestinal bleeding.
    • Vomiting preceded bleeding in most cases, with alcohol intake reported in 53%.
    • 40% of patients required blood transfusion, often with co-existing pathologies; surgery was not required.

    Conclusions:

    • The Mallory-Weiss lesion is a relatively common cause of upper gastrointestinal bleeding.
    • It is typically a benign condition, but can be severe if other pathological conditions are present.

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