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Related Experiment Videos

Radiological findings in total aganglionosis coli.

J F De Campo, V Mayne, D W Boldt

    Pediatric Radiology
    |January 1, 1984
    PubMed
    Summary

    Total colonic aganglionosis, a form of Hirschsprung's disease, presents with bowel obstruction in infants. Radiological findings vary, emphasizing the need for biopsy for definitive diagnosis.

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    Area of Science:

    • Pediatric Radiology
    • Gastrointestinal Surgery
    • Medical Imaging

    Background:

    • Total colonic aganglionosis is a severe form of Hirschsprung's disease.
    • Early diagnosis is crucial for effective management of congenital intestinal disorders.

    Purpose of the Study:

    • To review radiological findings in patients diagnosed with total colonic aganglionosis.
    • To evaluate the utility of barium enema in diagnosing this condition.

    Main Methods:

    • Retrospective review of radiological findings in 13 patients with total colonic aganglionosis.
    • Analysis of plain films and barium enema studies.

    Main Results:

    • All patients presented with plain film evidence of bowel obstruction.
    • Barium enema findings were non-specific, showing a spectrum of abnormalities including normal calibre colon, microcolon, shortened colon, colonic wall irregularity, and ileal reflux.
    • Delayed barium evacuation was noted in two cases.

    Conclusions:

    • Total colonic aganglionosis should be suspected in infants with plain film evidence of bowel obstruction, irrespective of barium enema findings.
    • Definitive diagnosis of Hirschsprung's disease and transition zone requires biopsy.

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