Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endoscopic laser endarterectomy.

G Van Stiegmann, D Kahn, A G Rose

    Surgery, Gynecology & Obstetrics
    |June 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Forty-Fourth Annual Meeting of the Mississippi Valley Association of Dental Surgeons.

    The Dental register·2021
    Same author

    Prosthetic Dentistry.

    The Dental register·2021
    Same author

    Minutes of Mississippi Valley Association of Dental Surgeons: Forty Third Annual Meeting, Cincinnati, March 2, 1887.

    The Dental register·2021
    Same author

    Pulmonary veno-occlusive disease associated with hypertrophic cardiomyopathy.

    Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
    Same author

    Pathology of chronic cardiac rejection: An analysis of the epicardial and intramyocardial coronary arteries and myocardial alterations in 43 human allografts.

    Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
    Same author

    Congenital stenotic arteriopathy with medial dysplasia of aorta, pulmonary artery, and their major branches.

    Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
    Same journal

    THE USE OF COMBINED PRESERVATION TECHNIQUES FOR EXTENDED STORAGE OF ORTHOTOPIC LIVER HOMOGRAFTS.

    Surgery, gynecology & obstetrics·2010
    Same journal

    The Role of Electrical Pacemakers in the Treatment of Unexpected Cardiac Arrest.

    Surgery, gynecology & obstetrics·2010
    Same journal

    Colonic and proctoscopic diseases.

    Surgery, gynecology & obstetrics·2010
    Same journal

    A summary of the surgical aspects of certain sulfonamides and antibiotic agents.

    Surgery, gynecology & obstetrics·2010
    Same journal

    Penetrating cranial wounds; a summary of methods used in management; collective review.

    Surgery, gynecology & obstetrics·2010
    Same journal

    The use of compression in the treatment of injuries.

    Surgery, gynecology & obstetrics·2010
    See all related articles

    The Neodymium YAG laser effectively ablates atheroma in air but is less effective in saline. Severe laser damage can lead to aneurysm formation, warranting further investigation into this laser therapy.

    Area of Science:

    • Vascular surgery
    • Laser medicine
    • Cardiovascular research

    Background:

    • Atherosclerosis poses significant risks to vascular health.
    • Minimally invasive treatments for atherosclerosis are in high demand.
    • Neodymium YAG laser (Nd:YAG) is a potential tool for atheroma removal.

    Purpose of the Study:

    • To evaluate the efficacy and safety of Nd:YAG laser ablation of atheroma.
    • To assess the impact of different environments (air vs. saline) on laser effectiveness.
    • To investigate potential complications, such as thrombosis and aneurysm formation.

    Main Methods:

    • Human cadaver aortoiliac arteries and normal porcine vessels were used.
    • Nd:YAG laser treatment was performed in both air and saline environments.

    Related Experiment Videos

  • Vascular endoscopy was utilized for in-situ treatment simulation.
  • Laser-treated vessel segments were examined for atheroma ablation, thrombosis, and tissue damage.
  • Long-term effects, including aneurysm formation, were monitored.

    • Main Results:

    • Nd:YAG laser effectively ablated atheroma in an air environment.
    • Laser efficacy was reduced when performed in saline, the environment required for vascular endoscopy.
    • No thrombogenicity was observed in laser-treated porcine arteries.
    • Severe laser damage, characterized by blanching and intimal elevation, consistently led to late aneurysm formation.

    Conclusions:

    • Nd:YAG laser ablation of atheroma is feasible, particularly in an air environment.
    • The reduced effectiveness in saline necessitates further research for endoscopic applications.
    • Careful control of laser energy is crucial to avoid severe damage and subsequent aneurysm formation.
    • Endoscopic laser endarterectomy (ELE) shows promise but requires further investigation.