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Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
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Familial intracranial gliomas

F B Maroun, J C Jacob, W D Heneghan

    Surgical Neurology
    |July 1, 1984
    PubMed

    Abstract:

    The pedigree of two interrelated families with 10 affected members suffering from malignant supratentorial gliomas is reported. In addition, three other unrelated families with two members each who were treated for different types of brain tumors are described. Genetic implications are discussed.

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