[Sodium, potassium, calcium and magnesium metabolism in patients with allergic-infectious bronchial asthma]

A total of 126 patients with infectious -- allergic bronchial asthma were studied, 56 males and 67 females, aged from 16 to 58 (average age 38,5), with a duration of the disease from 1 to 20 years, distributed into four groups: group 1 -- 33 patients with light stage of the disease, group II - 36 patients with moderately severe stage of the disease, group III -- severe stage of the disease (32 patients), group IV -- 25 patients with moderately severe and severe stage, treated with Ketotifen. Disorder of electrolyte metabolism was found in all patient groups with infectious-allergic bronchial asthma. Hyperpotassemia , hypermagnesiemia , hypernatremia and hypocalcemia were established with statistical significance. Various mechanisms participate in the pathogenesis-of those disorders, the allergic reaction being at the root. The electrolytic alterations depend on the stage and severity of the bronchial asthma. The electrolyte metabolism was favourably influenced after the treatment in all patient groups and pronounced - in the patients from group IV. That requires a proper drug treatment with a consideration given to the disturbed electrolytic balance.