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[Neonatal risk in early manifested maternal diabetes].
Zentralblatt Fur Gynakologie
|January 1, 1984
Summary
Maternal diabetes mellitus manifesting early (within 18 years) showed a trend toward increased neonatal mortality and malformations. However, increased neonatal morbidity risks were observed, similar to those in White Group B diabetic pregnancies.
Area of Science:
- Obstetrics and Gynecology
- Neonatology
- Endocrinology
Context:
- Maternal diabetes mellitus (DM) poses risks to neonatal outcomes.
- Early manifestation of DM in mothers (≤18 years) requires specific risk assessment.
- Comparison with late-manifesting DM groups (White B, C/D) is crucial for understanding disease progression impact.
Purpose:
- To estimate neonatal risks in pregnancies with early-onset maternal diabetes mellitus.
- To compare these risks with those in late-onset maternal diabetes mellitus.
- To identify specific neonatal morbidities associated with early maternal DM.
Summary:
- Analysis of 172 women with early-onset maternal DM over 10 years.
- Observed trends of increased neonatal mortality and malformations, though not statistically significant compared to late-onset groups.
- Demonstrated increased neonatal morbidity, including fetopathy, immaturity, and disturbed adaptation, also noted in White Group B pregnancies.
Impact:
- Highlights the need for vigilant monitoring of pregnancies with early-onset maternal DM.
- Suggests that certain neonatal morbidities in early-onset DM may share underlying mechanisms with those in later-onset DM.
- Informs clinical practice regarding risk stratification and management strategies for pregnant individuals with diabetes.