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Pulmonary coccidioidal mycetoma
The American Journal of the Medical Sciences
|May 1, 1984
Summary
Cavitary pulmonary disease from coccidioidomycosis is common, but fungus balls are rare. This case highlights a rare coccidioidal mycetoma as a late complication, requiring surgical intervention.
Area of Science:
- Mycology
- Pulmonary Medicine
- Infectious Diseases
Background:
- Cavitary pulmonary disease is a frequent manifestation of coccidioidomycosis.
- Fungal ball (mycetoma) formation within lung cavities caused by Coccidioides immitis is an exceptionally rare occurrence.
Observation:
- A unique case of coccidioidal mycetoma developed as a late sequela of primary pulmonary coccidioidomycosis.
- The patient experienced recurrent hemoptysis, necessitating a lobar resection due to treatment failure with amphotericin B.
Findings:
- Histologic examination revealed endosporulating spherules and septate mycelia with arthrospore formation, confirming Coccidioides immitis.
- The study details the medical and surgical management of this rare fungal ball complication.
Implications:
- This case underscores the importance of considering rare fungal ball formation in persistent or complicated coccidioidomycosis.
- The potential for human-to-human transmission from such lesions warrants further consideration in clinical management and public health.
- Advanced diagnostic and therapeutic strategies may be required for managing these uncommon sequelae.