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Endocarditis caused by Streptococcus morbillorum
Abstract:
Although patients with nutritionally variant streptococcal endocarditis have been reported in recent years, the specific clinical features of this disease have not been well characterized. We report here the clinical and laboratory features of a particularly unusual case of persistent bacteremia caused by Streptococcus morbillorum , one of the nutritionally variant streptococci. The patient was successfully treated with a combination of penicillin and rifampin after two treatment failures. We also review cases of nutritionally variant streptococcal endocarditis published in the English literature since 1971, in an attempt to understand some difficulties encountered in diagnosing and treating this type of endocarditis.
Insights
Nutritionally variant streptococcal endocarditis is rare and poorly understood. This case highlights successful treatment with penicillin and rifampin for persistent bacteremia caused by Streptococcus morbillorum.
Area of Science:
- Infectious Diseases
- Microbiology
- Cardiology
Background:
- Nutritionally variant streptococci (NVS) are an uncommon cause of infective endocarditis.
- The clinical presentation and optimal treatment strategies for NVS endocarditis remain poorly characterized.
Observation:
- This report details an unusual case of persistent bacteremia caused by Streptococcus morbillorum, a type of NVS.
- The patient experienced two treatment failures before successful management.
Findings:
- Successful treatment was achieved using a combination of penicillin and rifampin.
- A review of English literature since 1971 was conducted to analyze diagnostic and therapeutic challenges in NVS endocarditis.
Implications:
- This case contributes to understanding the clinical spectrum of NVS endocarditis.
- The findings suggest a potential treatment regimen for refractory NVS endocarditis, emphasizing the need for further research.