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Hyperprolactinemia, distress, and hostility.

R Kellner, M T Buckman, G A Fava

The American Journal of Psychiatry

|June 1, 1984

Summary

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Women with hyperprolactinemia show elevated hostility, depression, and anxiety, similar to psychiatric patients. Researchers recommend prolactin level testing for women with these symptoms.

Area of Science:

Endocrinology
Psychiatry
Women's Health

Background:

Hyperprolactinemia, a condition of elevated serum prolactin, is associated with various physical and psychological symptoms.
The psychological impact of hyperprolactinemia requires further investigation, particularly in relation to common psychiatric presentations.

Purpose of the Study:

To compare the psychological symptom profiles of women with hyperprolactinemia to those of other patient and non-patient groups.
To identify specific psychological symptoms that may indicate hyperprolactinemia in women.

Main Methods:

A comparative study involving 14 women diagnosed with hyperprolactinemia.
Symptom assessment using the Symptom Rating Test and Symptom Questionnaire.
Comparison groups included nonpsychotic psychiatric patients, family practice patients, and healthy female employees.

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Main Results:

Women with hyperprolactinemia reported significantly higher levels of hostility, depression, and anxiety compared to family practice patients and non-patient employees.
Symptom scores for hyperprolactinemic women were comparable to those of women attending a psychiatric clinic.
Increased feelings of inadequacy were noted in the hyperprolactinemic group.

Conclusions:

Hyperprolactinemia may present with psychological symptoms overlapping with those seen in psychiatric disorders.
Measurement of serum prolactin levels is recommended for women exhibiting depression, hostility, anxiety, and other signs suggestive of hyperprolactinemia.