Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dangerous asthma.

A C Dornhorst

    Aviation, Space, and Environmental Medicine
    |May 1, 1984
    PubMed
    Summary

    Severe asthma attacks involve more than bronchoconstriction, including dangerous airway inflammation and mucus plugs. Recognizing these severe asthma symptoms promptly can prevent fatalities in young adults.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pulmonary collapse and consolidation; the role of collapse in the production of lung field shadows and the significance of segments in inflammatory lung disease.

    The Journal of the Faculty of Radiologists. Faculty of Radiologists (Great Britain)·2014
    Same author

    Diphtheria.

    Proceedings of the Conference of Army Physicians, Central Mediterranean Forces : held at the Institute superiore di sanita : Rome, 29th January to 3rd February 1945. Conference of Army Physicians, Central Mediterranean Forces (1945 : Is...·2010
    Same author

    A prospective view.

    Proceedings of the Royal Society of Medicine·2010
    Same author

    Pathology: is it well taught? A physician's view.

    Journal of the Royal Society of Medicine·1991
    Same author

    Seeing eye to eye.

    Nature·1987
    Same author

    Analysis of red cell survival data.

    British journal of haematology·1987

    Area of Science:

    • Pulmonology
    • Critical Care Medicine

    Background:

    • Severe asthma attacks contribute to a significant number of preventable deaths, particularly in young, otherwise healthy individuals.
    • Misdiagnosis of severe asthma attacks, often presumed to be solely bronchoconstriction, delays critical interventions.
    • Pathophysiology of severe asthma involves bronchial hyperaemia, plasma exudation, and mucus plugging, leading to airway obstruction.

    Purpose of the Study:

    • To enhance awareness of the multifaceted pathology in severe asthma attacks.
    • To reduce mortality rates associated with severe asthma exacerbations.
    • To educate on recognizing critical signs beyond simple bronchoconstriction.

    Main Methods:

    • Review of clinical presentations and outcomes in severe asthma attacks.
    • Analysis of pathophysiological mechanisms contributing to severe asthma exacerbations.
    • Evaluation of diagnostic challenges and treatment delays.

    Main Results:

    • Severe asthma attacks involve complex airway inflammation, plasma leakage, and mucus plug formation, not just bronchoconstriction.
    • Delayed recognition of these severe conditions increases mortality risk.
    • Damage to bronchial epithelium during attacks prolongs recovery and heightens susceptibility to subsequent events.

    Conclusions:

    • Increased clinical awareness of severe asthma attack pathophysiology is crucial for reducing mortality.
    • Prompt medical consultation is advised when bronchodilator effectiveness diminishes in degree or duration.
    • Understanding the full spectrum of severe asthma, including inflammation and mucus plugging, is vital for timely and effective management.

    Related Experiment Videos