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Short-contact dithranol therapy--a comparison with the Ingram regime
The British Journal of Dermatology
|June 1, 1984
Summary
The Ingram regimen for plaque psoriasis offered faster improvement than short-contact dithranol. However, both treatments showed identical relapse rates after 12 weeks, with short-contact dithranol causing more irritation.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Plaque psoriasis is a chronic inflammatory skin condition.
- Dithranol and Ingram regimens are established treatments for psoriasis.
Purpose of the Study:
- To compare the efficacy and side effects of short-contact dithranol therapy versus the traditional Ingram regimen for plaque psoriasis.
Main Methods:
- A comparative study involving forty-three patients with plaque psoriasis.
- Treatment groups received either short-contact dithranol or the Ingram regimen.
- Patient outcomes and relapse rates were monitored.
Main Results:
- The Ingram regimen demonstrated a significantly faster rate of psoriasis improvement compared to short-contact dithranol.
- No significant difference in relapse rates was observed between the two groups at 12 weeks post-treatment.
- Short-contact dithranol therapy was associated with a more troublesome irritant effect.
Conclusions:
- While the Ingram regimen provides quicker results, both treatments yield similar long-term relapse rates for plaque psoriasis.
- Short-contact dithranol may be a viable option for home treatment despite potential irritation.