Identification of a plasma metabolite of 5-(2-bromo-E-ethenyl)-2'-deoxyuridine

A prominent plasma metabolite was detected in animals and man after oral administration of 5-(2-bromo-E- ethenyl )-2'-deoxyuridine. The metabolite was isolated by solvent extraction and high-performance liquid chromatography and was identified by mass spectrometry as 5-(2-bromo-E- ethenyl )uracil.