Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changes in human skeletal muscle induced by long-term eccentric exercise.

J Fridén

    Cell and Tissue Research
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The state of the art in beyond 5G distributed massive multiple-input multiple-output communication system solutions.

    Open research Europe·2023
    Same author

    Outcomes of reconstructive hand surgery in patients with tetraplegia and neuropathic pain.

    Spinal cord·2018
    Same author

    Morphological patterns of the pretendinous cord in Dupuytren's disease: a predictor of clinical outcome?

    Journal of plastic surgery and hand surgery·2018
    Same author

    Ultrasonographic examination of the ruptured cord after collagenase treatment or needle fasciotomy for Dupuytren's contracture.

    The Journal of hand surgery, European volume·2017
    Same author

    Essential gains and health after upper-limb tetraplegia surgery identified by the International classification of functioning, disability and health (ICF).

    Spinal cord·2017
    Same author

    Satisfaction with upper limb reconstructive surgery in individuals with tetraplegia: the development and reliability of a Swedish self-reported satisfaction questionnaire.

    Spinal cord·2017
    Same journal

    Correction to: Integrated morphological analyses of Cladomorphus phyllinus and transcriptomic analysis of Cladomorphus trimariensis provide insights into the cardiac morphophysiology of stick insects (Phasmida: Phasmatidae).

    Cell and tissue research·2026
    Same journal

    Deletion of CEACAM1 does not affect retinal and choroidal morphology or transcriptome.

    Cell and tissue research·2026
    Same journal

    Cardiac α2δ1 C-terminal contributes to left atrial hypertrophy in chronic ischemic heart failure, in association with changes in membrane GluN1 and p-CAMKII/p-HDAC4 signaling.

    Cell and tissue research·2026
    Same journal

    Gill ionocytes of the Lake Magadi tilapia (Oreochromis Alcolapia grahami), an extremophilic teleost native to a highly alkaline environment.

    Cell and tissue research·2026
    Same journal

    Integrated morphological analyses of Cladomorphus phyllinus and transcriptomic analysis of Cladomorphus trimariensis provide insights into the cardiac morphophysiology of stick insects (Phasmida: Phasmatidae).

    Cell and tissue research·2026
    Same journal

    Effects of gestational protein restriction on autophagy dynamics during odontogenesis.

    Cell and tissue research·2026
    See all related articles

    High-tension eccentric training caused significant muscle fiber changes, particularly in fast-twitch fibers. This reorganization enhances muscle stretchability and reduces injury risk.

    Area of Science:

    • Exercise physiology
    • Muscle biology
    • Cellular adaptation

    Background:

    • Muscle fibers undergo structural changes in response to training.
    • Eccentric exercise places high tension on muscles, potentially leading to micro-damage and adaptation.

    Purpose of the Study:

    • To investigate the ultrastructural changes in muscle fibers after a two-month eccentric training program.
    • To compare these changes with non-exercised controls.

    Main Methods:

    • Electron microscopy was used to examine muscle fiber fine structure.
    • Comparison of muscle specimens from trained individuals and sedentary controls.

    Main Results:

    • Eccentric training induced alterations in myofibrillar architecture, including Z-band abnormalities and extra sarcomeres.

    Related Experiment Videos

  • Type-2 (fast-twitch) fibers were predominantly affected, showing increased variation in sarcomere length.
  • Ultrastructural changes included Z-band disorganization and the presence of myofilaments, glycogen, and ribosomes between separated Z-bands.

    • Conclusions:

    • High-tension muscular work, particularly eccentric training, causes significant fine-structural alterations in muscle fibers.
    • These adaptations, especially in Type-2 fibers, likely improve muscle stretchability and reduce mechanical damage.
    • The observed reorganization optimizes actin-myosin filament overlap for improved muscle function.