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Related Experiment Videos

Computerized quantitative analysis of left ventricular wall motion by two-dimensional echocardiography.

I Schnittger, P J Fitzgerald, E P Gordon

    Circulation
    |August 1, 1984
    PubMed
    Summary

    Accurate quantitative analysis of left ventricular wall motion using two-dimensional echocardiography requires optimal reference systems. This study identified the best methods for different views, improving diagnostic accuracy for wall motion abnormalities.

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    Area of Science:

    • Cardiology
    • Medical Imaging
    • Biomedical Engineering

    Background:

    • Quantitative analysis of left ventricular segmental wall motion abnormalities is crucial for diagnosis.
    • The accuracy of such analysis is highly dependent on the chosen reference system due to dynamic cardiac geometry and motion.
    • Existing methods face challenges in accounting for translation and rotation during cardiac cycles.

    Purpose of the Study:

    • To assess the feasibility and accuracy of quantitative left ventricular wall motion analysis using two-dimensional echocardiography.
    • To evaluate various reference systems for their effectiveness in analyzing wall motion.
    • To develop a computerized system for unbiased selection of optimal analysis methods.

    Main Methods:

    • Studied 61 subjects using 44 different reference methods across three echocardiographic views (apical four-chamber, parasternal short-axis at mitral valve, parasternal short-axis at papillary muscles).

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  • Categorized reference systems into fixed external, floating (translation correction), and those correcting for both translation and rotation.
  • Utilized computerized analysis of end-diastolic and end-systolic outlines, calculating fractional shortening of radial dimensions and fractional change in area measurements.

    • Main Results:

    • A floating-reference system correcting for translation was optimal for apical four-chamber and mitral valve parasternal short-axis views.
    • A fixed external reference system was optimal for the papillary muscle level parasternal short-axis view.
    • Area and radial dimension methods showed comparable sensitivity and specificity across different angular intervals; day-to-day variations were 7-13%.

    Conclusions:

    • A computerized system can objectively select optimal reference methods for two-dimensional echocardiographic analysis of left ventricular wall motion.
    • The choice of reference system significantly impacts the accuracy of quantitative wall motion analysis.
    • This approach enhances the reliability of diagnosing left ventricular segmental wall motion abnormalities.