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Updated: Aug 12, 2026

Single-unit In vivo Recordings from the Optic Chiasm of Rat
Published on: April 2, 2010
Abstract:
Ketamine was used on 80 occasions to induce anaesthesia in 77 animals. Xylazine premedication was used alone on 75 occasions, in conjunction with methadone once, in conjunction with methadone and acepromazine once and, on three occasions, methadone and acepromazine only were used. Anaesthesia was maintained in seven cases with halothane and oxygen. Premedication with xylazine 5 mins previously or concurrently with ketamine gave similar results but an interval of more than 5 mins between the drugs produced less deep anaesthesia and this protocol is, therefore, not advised. Induction and recovery were judged to be good in 82 per cent and 78 per cent of cases, respectively, and analgesia and muscle relaxation were judged as adequate in 79 per cent of cases.

