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[2,5-diaryl-substituted 1,3,4-oxadiazoles: synthesis and preliminary pharmacological investigation]
Abstract:
Seven 2,5-diarylalkyloxysubstituted 1,3,4-oxadiazoles were synthesized. They showed pronounced antiphlogistic action together with central activity (sedative, analgesic) that principally seems to be connected with the presence in the molecule of the 3,4-dioxymethylenephenyl radical.