Related Experiment Video

Updated: Aug 19, 2026

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury
10:25

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury

Published on: August 30, 2011

Renal medullary necrosis in infants and children

K Kozlowski, R W Brown

    Pediatric Radiology
    |June 19, 1978
    PubMed

    Insights

    Renal medullary necrosis can occur in infants and children, particularly those with a history of kidney hypoxia. Radiologists should consider this diagnosis in pediatric patients presenting with relevant clinical signs.

    Area of Science:

    • Pediatric Nephrology
    • Diagnostic Radiology
    • Medical Imaging

    Background:

    • Renal medullary necrosis is a rare condition affecting the kidneys.
    • Early diagnosis is crucial for appropriate management in pediatric cases.

    Observation:

    • Two infant cases of renal medullary necrosis were identified via excretory urography.
    • A retrospective review identified 24 pediatric cases diagnosed at autopsy between 1953 and 1977.

    Findings:

    • Excretory urography can aid in the diagnosis of renal medullary necrosis in infants.
    • Autopsy data confirms the occurrence of renal medullary necrosis in children.

    Implications:

    • Radiologists should maintain a high index of suspicion for renal medullary necrosis in children with a history of kidney hypoxia.
    • Awareness of this entity can improve diagnostic accuracy and patient outcomes.

    More Related Videos

    Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis06:09

    Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

    Published on: July 18, 2017

    A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis05:39

    A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

    Published on: November 30, 2021

    Related Concept Videos

    Acute Kidney Injury I: Introduction01:22

    Acute Kidney Injury I: Introduction

    Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
    Acute Kidney Injury II: Pathophysiology01:29

    Acute Kidney Injury II: Pathophysiology

    Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
    Acute Kidney Injury III: Clinical Manifestations01:29

    Acute Kidney Injury III: Clinical Manifestations

    Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
    Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

    Acute Kidney Injury IV: Diagnostic Studies and Prevention

    Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
    Acute Kidney Injury V: Interprofessional Care01:20

    Acute Kidney Injury V: Interprofessional Care

    Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...