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Cold pressor test as a predictor of hypertension
Hypertension (Dallas, Tex. : 1979)
|May 1, 1984
Summary
The cold pressor test, a measure of blood pressure response to cold, can predict future hypertension. Early hyperreactors showed significantly higher rates of developing high blood pressure over 45 years.
Area of Science:
- Cardiology
- Hypertension Research
- Predictive Medicine
Background:
- Hypertension is a major global health concern.
- Predictive markers for hypertension are crucial for early intervention.
- The cold pressor test (CPT) has been investigated for its predictive potential.
Purpose of the Study:
- To evaluate the cold pressor test's utility in predicting the development of hypertension.
- To assess the long-term relationship between cold pressor test reactivity and future blood pressure levels.
Main Methods:
- A longitudinal study comparing blood pressure in 142 patients from 1979 with CPT results from 1934 and 1961.
- Subjects were categorized as hyperreactors or normoreactors based on CPT responses.
- Follow-up extended for 45 years, with a mean age of nearly 57 years at the final assessment.
Main Results:
- Hypertension developed in 71% of hyperreactors versus 19% of normoreactors.
- Hyperreactors were more likely to reach higher blood pressure strata (Stratum 1: 140-160 mmHg systolic or 90-100 mmHg diastolic; Stratum 2: >160 mmHg systolic or >100 mmHg diastolic).
- Antihypertensive therapy was more common in hyperreactors.
Conclusions:
- Early abnormal response to the cold pressor test is associated with a significantly higher risk of developing hypertension later in life.
- The cold pressor test may serve as a valuable indicator for predicting future hypertension.
- This study provides long-term evidence supporting the predictive value of the cold pressor test.