Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aortic valve replacement in elderly patients.

Y Glock, R Pecoul, A Cerene

    The Journal of Cardiovascular Surgery
    |May 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Annals of burns and fire disasters·2017
    Same author

    Long-term outcomes following repair or replacement in degenerative mitral valve disease.

    The Thoracic and cardiovascular surgeon·2010
    Same author

    [Cardiac tumors: CT and MR imaging features].

    Journal de radiologie·2010
    Same author

    [Cervical aortic arch and ectopic origin of the left coronary ostium].

    Journal de radiologie·2010
    Same author

    Neurological pictures. Stroke with calcium emboli related to a calcified stenosis of internal carotid artery.

    Journal of neurology, neurosurgery, and psychiatry·2008
    Same author

    Oxygen-regulated protein-150 prevents calcium homeostasis deregulation and apoptosis induced by oxidized LDL in vascular cells.

    Cell death and differentiation·2008
    Same journal

    Pelvic venous disease and lymphatic dysfunction: evaluating the evidence for a proposed continuum.

    The Journal of cardiovascular surgery·2026
    Same journal

    Incidence of post-dissection aneurysmal formation and need for secondary intervention after surgery for acute type A aortic dissections: a systematic review and meta-analysis of observational studies.

    The Journal of cardiovascular surgery·2026
    Same journal

    The expertise effect: how advancing skills in frozen elephant trunk have broadened surgical indication for acute dissection.

    The Journal of cardiovascular surgery·2026
    Same journal

    Outcomes of pulmonary embolism response teams: a systematic review.

    The Journal of cardiovascular surgery·2026
    Same journal

    Use of large bore devices in the treatment of pulmonary embolism.

    The Journal of cardiovascular surgery·2026
    Same journal

    Contemporary role of systemic thrombolysis in the management of acute pulmonary embolism.

    The Journal of cardiovascular surgery·2026
    See all related articles

    Elderly patients undergoing aortic valve replacement (AVR) showed significant functional improvement. Despite risks, 93% of survivors improved to New York Heart Association class I or II, demonstrating AVR

    Area of Science:

    • Cardiovascular Surgery
    • Geriatric Cardiology
    • Biomaterials and Medical Devices

    Background:

    • Aortic valve replacement (AVR) is a critical procedure for elderly patients with severe aortic valve disease.
    • Patients aged 70+ often present with advanced New York Heart Association (NYHA) functional class III/IV, high rates of angina, and syncope.
    • Optimal management strategies for AVR in the elderly remain an area of active investigation.

    Purpose of the Study:

    • To report the outcomes of aortic valve replacement (AVR) in elderly patients (aged 70+) with severe aortic valve disease.
    • To evaluate the safety and efficacy of tilting disk valves in this high-risk population.
    • To assess long-term survival, functional status, and complication rates following AVR.

    Main Methods:

    Related Experiment Videos

  • Retrospective analysis of 62 consecutive patients aged 70 or more undergoing AVR between 1970 and 1982.
  • Patients presented with NYHA functional class III (29%) or IV (71%), with diagnoses including aortic stenosis, regurgitation, or mixed disease.
  • Tilting disk valves were implanted, with patients managed on either warfarin anticoagulation (80%) or antiplatelet therapy (20%).

    • Main Results:

    • The operative myocardial infarction rate was 6.4%.
    • Late mortality was 22.6% (4.8% cardiac deaths) over a mean follow-up of 26 months.
    • 93% of surviving patients improved to NYHA class I or II, with a 5-year survival probability of 71%.

    Conclusions:

    • Aortic valve replacement (AVR) in elderly patients (70+) significantly improves functional status and survival.
    • Tilting disk valves demonstrated acceptable thromboembolic (1.6%) and disinsertion (3.2%) rates in this cohort.
    • Despite operative risks and late mortality, AVR offers substantial long-term benefits for selected elderly patients with severe aortic valve disease.