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Updated: Aug 19, 2026
Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
Femoral-femoral bypass. Non-invasive hemodynamic evaluation
Insights
Femoral-femoral bypass surgery improved recipient limb blood flow, as shown by increased ankle/arm index. Donor limb pressure slightly decreased, but this was not clinically significant. Angiography did not predict outcomes.
Area of Science:
- Vascular Surgery
- Hemodynamics
- Non-invasive Vascular Assessment
Background:
- Femoral-femoral bypass grafts are used to treat peripheral arterial disease.
- Understanding the hemodynamic impact of these grafts is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the hemodynamic effects of femoral-femoral bypass grafts.
- To determine if preoperative angiographic findings predict postoperative results.
Main Methods:
- Seven patients undergoing femoral-femoral bypass were assessed.
- Preoperative angiography and pre/postoperative non-invasive vascular studies were performed.
- Ankle/arm (a/a) index was measured in both donor and recipient limbs.
Main Results:
- Recipient extremity a/a index significantly increased (0.39 to 0.74, p<0.02).
- Donor extremity a/a index showed a non-significant decrease (0.82 to 0.70).
- One patient experienced "steal" syndrome; no correlation found between angiography and outcomes.
Conclusions:
- Femoral-femoral bypass significantly improves recipient limb hemodynamics.
- Donor limb pressure changes are generally clinically insignificant.
- Angiography is not predictive of postoperative outcomes in this cohort.
Abstract:
Seven patients who underwent femoral-femoral by pass between June 1980 and September 1982 underwent pre-operative angiography and pre and post-operative non-invasive evaluation to determine: (1) the hemodynamic effects created by the crossover graft, and (2) if angiographic findings would be predicative of post-operative results. The mean ankle/arm (a/a) index in the donor extremity changed from 0.82 +/- 0.20 to 0.70 +/- 0.27 (NS). The a/a index in the recipient extremity increased from 0.39 +/- 0.30 to 0.74 +/- (p less than 0.02). One patient developed a "steal" syndrome. There was no correlation between angiographic findings and post-operative changes. This study demonstrated a significant increase in recipient extremity ankle pressure and a clinically insignificant decrease in donor limb pressure.
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