Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Status epilepticus after baclofen withdrawal.

C L Hyser, M E Drake

    Journal of the National Medical Association
    |May 1, 1984
    PubMed
    Summary

    Baclofen withdrawal can rarely cause serious neurological issues like status epilepticus. Gradual dose reduction is advised to prevent these severe baclofen side effects.

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A simplified inlay technique.

    Dental digest·2010
    Same author

    Pediatric migraine prophylaxis with divalproex.

    Journal of child neurology·2001
    Same author

    Can current EMS dispatch protocols identify layperson-reported sentinel conditions?

    Prehospital emergency care·2000
    Same author

    Do emergency medical services dispatch nature and severity codes agree with paramedic field findings?

    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine·2000
    Same author

    Electrophysiologic assessment of autonomic function in epilepsy.

    Seizure·1998
    Same author

    Interictal quantitative EEG in epilepsy.

    Seizure·1998

    Area of Science:

    • Neurology
    • Pharmacology

    Background:

    • Baclofen is a common treatment for spasticity.
    • It is generally well-tolerated with few side effects.

    Observation:

    • Adverse events like agitation and hallucinations can occur upon abrupt baclofen withdrawal.
    • Previous reports include seizures following baclofen discontinuation.

    Findings:

    • This paper details a case of status epilepticus after baclofen withdrawal.
    • The patient also suffered hypoxic cerebral injury.

    Implications:

    • This case highlights rare but severe neurological complications of baclofen withdrawal.
    • Gradual dosage adjustments are crucial for patient safety during baclofen therapy.