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Updated: Jul 27, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Abstract:
Of 33 patients with psychogenic cough tic, 31 were successfully treated using an unusual reinforced suggestion technique. The cough usually follows an incidental upper respiratory tract infection and persists as a loud paroxysmal barking or honking sound for weeks to months. Paroxysms occur all day but cease with sleep. The diagnosis is often delayed for weeks to months while the patient is exposed to an increasing intensity of diagnostic procedures and therapy. Thirty percent of some 20 patients previously reported in the literature had been hospitalized. The reinforced suggestion technique depends upon the physician's convincing the patient that the persistent cough has weakened the chest muscles, which are now unable to contain the cough, and that a bedsheet tightly wrapped around the chest will provide the necessary support to stop the cough within 24 to 48 hours. The typical patient can produce the cough on command, has an ambivalent response to the prospect of care, is unconcerned about his symptoms, submits willingly to the examination and procedures, and is kept out of school for the duration of the cough. Findings on physical examination are normal except for abnormal gag and corneal reflexes. The gag reflex was depressed in six and absent in 20 of the 31 patients. The corneal reflex was depressed in 16 and absent in 5 of the 31 patients. These abnormal responses help to corroborate the psychogenic etiology. Early recognition of the nonorganic nature of this syndrome will reduce parental anxiety, loss of school time, risk of iatrogenic complications, and unnecessary medical and hospital expense.
Insights
A novel reinforced suggestion technique successfully treated 31 of 33 patients with psychogenic cough tic. This method involves physician-led suggestion and chest wrapping to support weakened muscles, resolving the cough within days.
Area of Science:
- Pediatric Pulmonology
- Psychosomatic Medicine
- Behavioral Neurology
Background:
- Psychogenic cough tic, often following a viral infection, presents as a persistent, loud barking or honking cough.
- Diagnosis is frequently delayed, leading to extensive investigations and potential iatrogenic complications.
- Previous literature reported significant hospitalization rates for similar cases.
Observation:
- Patients exhibit a characteristic cough, often producible on command, with normal physical findings except for abnormal gag and corneal reflexes.
- The cough is pervasive throughout the day but absent during sleep.
- Patients may display indifference to their symptoms and ambivalence towards treatment.
Findings:
- A reinforced suggestion technique, utilizing physician conviction and chest wrapping, achieved a 94% success rate in treating psychogenic cough tic.
- The technique posits that chest muscles are weakened, requiring external support from a tightly wrapped bedsheet.
- Abnormal gag and corneal reflexes were observed in a majority of patients, supporting a psychogenic etiology.
Implications:
- Early identification of psychogenic cough tic can prevent unnecessary medical interventions, hospitalizations, and associated costs.
- This approach can significantly reduce parental anxiety and minimize school absenteeism.
- The findings highlight the efficacy of behavioral interventions in managing functional neurological disorders.
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