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[Changes in the mitral echogram in ischemic heart disease]
Insights
Mitral echogram changes in ischemic heart disease (IHD) patients correlate with left ventricular dysfunction. Echocardiogram (EChO-C) indices reveal significant alterations, particularly in those with left ventricular insufficiency, impacting heart function.
Area of Science:
- Cardiology
- Echocardiography
- Cardiovascular Physiology
Background:
- Ischemic heart disease (IHD) often presents with elevated left ventricular end-diastolic pressure (LVEDP).
- Pathological changes in LVEDP, ventricular contraction, and left ventricular (LV) wall compliance can alter mitral echogram parameters.
- Mitral echogram analysis offers insights into cardiac function in IHD patients.
Purpose of the Study:
- To compare mitral echogram parameters between healthy subjects and patients with chronic IHD.
- To investigate the correlation between mitral echogram indices and left ventricular function in IHD.
- To identify echocardiographic markers indicative of cardiac dysfunction in IHD.
Main Methods:
- A clinical-paraclinical study involving 60 patients with chronic IHD and a control group of healthy subjects.
- Statistical-variation analysis of mitral echogram amplitudes and diastolic velocity parameters.
- Echocardiogram (EChO-C) assessment of mitral echogram, LV dimensions, and pump/contractile function (EF, FS, CFC, SV, MV).
Main Results:
- In IHD patients without left ventricular insufficiency, EChO-C indices were within normal limits.
- Patients with IHD and left ventricular insufficiency (Stage II) exhibited significantly altered mitral echogram EChO-C indices.
- These mitral echogram changes correlated with increased LV dimensions, elevated LVEDP, and reduced LV contractile function indices.
Conclusions:
- Mitral echogram alterations are significant indicators of cardiac dysfunction in IHD patients, especially those with left ventricular insufficiency.
- Echocardiographic assessment of the mitral echogram provides valuable information on the severity of IHD and associated LV dysfunction.
- EChO-C indices of the mitral echogram serve as reliable markers correlating with established measures of LV pump and contractile function.
Abstract:
The patients with ischemic heart disease (IHD) have usually elevated end diastolic pressure (in the left ventricle (LVEDP). Such a change in LVEDP and to a certain extent the pathological ventricular contraction and the reduced compliance of the LV wall lead to definite pathological changes in the mitral echogram. The values, obtained by statistical-variation analysis, of the amplitudes and the velocity diastolic parameters of the mitral echogram in the group of the healthy subjects were compared with those of 60 patients with chronic IHD. A complex clinical-paraclinical study was carried out with the selected groups of healthy subjects and patients with IHD. It was established, that in patients with IHD without left ventricular insufficiency, EChO-C indices characterizing the mitral echogram, as well as EChO-C indices of the pump and contractile function of the left ventricle showed no value deviations from the norm. In the other two groups of patients with IHD the following was established; pathologically changed values of EChO-C indices reflecting the motion, amplitude and velocity parameters of the mitral echogram, more significantly manifested in patients with IHD with left ventricular insufficiency, II Stage. That EChO-C konstellation of the mitral echogram, correlates well with the increased end diastolic and systolic dimensions, left ventricular end diastolic pressure and left auricular systolic dimensions as well as with the reduced values of EChO-C indices of the pump and contractile function of the left ventricle: EF, FS (%), CFC, SV and MV.