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Updated: Jun 25, 2026

Non-invasive Parenchymal, Vascular and Metabolic High-frequency Ultrasound and Photoacoustic Rat Deep Brain Imaging
Published on: March 2, 2015
[Ultrasonic method of studying intracranial blood and cerebrospinal fluid dynamics in healthy subjects and in
Abstract:
A noninvasive ultrasonic method of brain biolocation with the sensor positioned in the region of the frontal eminences, was developed. The selected signal from an immobile structure, the occipital bone, is registered graphically. The method allows the cerebral hemispheres to be studied separately, yields information which is more precise than that obtained by means of the commonly known methodical approaches, and provides data on the intracranial dynamics of blood and cerebrospinal fluid. The results of the study provide evidence of a statistically significant (P less than 0.05) shift in the index of ultrasonics pulsed fading (alpha p) in healthy individuals and in patients with cerebral lesions and changes in the functional and neurological state. To verify the noninvasive methods parallel studies were conducted by means of the invasive method.

