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The effect of metrizamide on regional brain glucose metabolism in the rat
Acta Neurologica Scandinavica
|April 1, 1984
Abstract:
The X-ray contrast material metrizamide is structurally related to 2-deoxyglucose and inhibits brain glucose phosphorylation in vitro. In vivo, the present autoradiographic study with labeled 2-deoxyglucose revealed a global reduction of brain glucose phosphorylation after metrizamide administration in the cisterna magna of rats. The reduction averaged 18% of all regions.