Human cervical cancer clearance after 252Cf neutron brachytherapy versus conventional photon brachytherapy

Tumor clearance pattern was studied for Stage IB carcinoma of the cervix using 252Cf neutron brachytherapy followed by fractionated radiotherapy as compared to conventional therapy using fractionated radiotherapy followed by 137Cs photon low-dose rate (LDR) implant therapy. Reduction in bulk of tumor was assessed by regular and frequent serial clinical observations. The tumor clearance pattern of the neutron-treated patients was greatly accelerated and radically different from those treated using conventional radiation.