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Gout in South African blacks.

G M Mody, P D Naidoo

    Annals of the Rheumatic Diseases
    |June 1, 1984
    PubMed
    Summary

    This study analyzed gout cases in Black patients in Durban, South Africa, finding polyarthritis and knee involvement common. Secondary gout was linked to hypertension and diuretic use in 42% of patients.

    Area of Science:

    • Rheumatology
    • Epidemiology
    • Internal Medicine

    Background:

    • Gout is a common inflammatory arthritis.
    • Understanding its presentation in specific populations is crucial for effective management.
    • Black patients in South Africa represent a unique demographic for gout research.

    Purpose of the Study:

    • To determine the frequency, age of onset, presentation, joint involvement, and types of gout (primary vs. secondary) in Black patients.
    • To analyze hospital admission rates for gout in this population.
    • To identify potential risk factors for secondary gout.

    Main Methods:

    • Retrospective study design.
    • Analysis of hospital admissions for gout over a 5-year period (1977-1981).
    • Data collection on patient demographics, clinical presentation, joint involvement, serum uric acid levels, and comorbidities.

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    Main Results:

    • Gout admission rate was 4.7 per 100,000 hospital admissions.
    • Polyarthritis (74%) was more common than monoarthritis (26%) at admission.
    • Frequently affected joints included knees (74%), first metatarsophalangeal (MTP) joint (58%), and ankles (42%).
    • Elevated serum uric acid (SUA) was observed in 94% of patients.
    • Tophi were clinically present in 47%.
    • Secondary gout was identified in 42% of patients, primarily associated with hypertension and diuretic use.

    Conclusions:

    • Gout in Black patients in Durban presented frequently with polyarthritis and involved the knees, MTP joints, and ankles.
    • A significant proportion of secondary gout cases were linked to hypertension and diuretic treatment.
    • Further research into the specific etiological factors and management strategies for gout in this population is warranted.