[Adrenergic structures and monoamine oxidase activity in dystrophic skeletal muscles]

Patients with Duchenne's progressive muscular dystrophy show a high catecholamine content in the adrenergic structures and low mitochondrial monoamine oxidase activity in the skeletal muscles. Activation of dopamine deamination in the mitochondria-surrounding medium may be accounted for by the damage te mitochondrial membrane permeability. Patients with Charcot-Marie's neural amyotrophy did not manifest any such alterations.