Postnatal undernutrition: effect on antral gastrin levels at a later age

In rats undernutrition from birth to 14 days of age resulted in retardation of growth and diminution of antral gastrin concentration. When the 14-day-old undernourished rats were nutritionally rehabilitated, they grew at a faster rate, and at 27 days of age their body weight and the weight of various tissues of the gastrointestinal tract including the antrum reached the levels of the well-nourished littermate controls. In spite of this, antral gastrin concentration was found to be about one-half of that of the well-nourished littermates.