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Related Experiment Videos

Prolactin concentrations in mouse milk during lactation.

R C Richards, J M Beardmore

    Experientia
    |July 15, 1984
    PubMed
    Summary

    Prolactin levels in mouse milk peak two to three days after birth, reaching 230 ng/ml. These hormone concentrations then decrease to 140 ng/ml by day six and remain stable until the pups are weaned.

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    Area of Science:

    • Reproductive biology
    • Mammalian lactation physiology

    Background:

    • Prolactin is a key hormone regulating lactation in mammals.
    • Understanding prolactin dynamics is crucial for studying maternal-infant interactions and developmental processes.

    Purpose of the Study:

    • To quantify prolactin levels in mouse milk throughout the lactation period.
    • To establish a reference profile for prolactin concentration in lactating mice.

    Main Methods:

    • Mouse milk samples were collected at various time points post-parturition.
    • Prolactin concentrations were measured using a validated assay.

    Main Results:

    • Milk prolactin levels increased significantly from parturition, reaching a peak of 230 ng/ml on days 2 and 3 of lactation.
    • Following the peak, prolactin levels decreased to 140 ng/ml by day 6.
    • These reduced levels were sustained until the weaning period.

    Conclusions:

    • Mouse milk prolactin exhibits a distinct temporal pattern during lactation, with an early peak and subsequent decline.
    • This profile provides essential data for research on milk composition and hormonal regulation in mice.

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