Effects of repeated sampling on the properties of the cervical mucus during one day at midcycle

Midcycle cervical secretions were collected every hour from 08.00 to 12.00 h in 12 normal women. There was a significant decrease in gram wet weight of mucus in the first four samples followed by an increase in the fifth specimen (trend analysis). Spinnbarkeit decreased significantly during repeated sample collection. Albumin concentration in cervical secretion increased significantly during repeated sample collection, but there was no statistically significant difference in the total amount of albumin recovered during repeated sample collection. The possibility of a hormonal regulation of the water content in the cervical mucus is discussed.