[Treatment of ergotism]
Related Experiment Video
Updated: Oct 9, 2026

Exploring the Two Herb Combination Strategy to Treat Injured PC12 Cells
Published on: November 18, 2022
Abstract:
Ergotism occurs in patients so disposed, particularly under ergotamine therapy for migraine. The principal signs are arterial spasms in the legs, or sometimes also the arms, which can lead to gangrene. Intravenous or intra-arterial infusion of sodium nitroprusside or nitroglycerine has proved the only reliably efficacious therapy. The best results have been obtained using nitroprusside: twelve cases are described here. By contrast, nonefficacious measures include, in particular, sympathetic blockade.
More Related Videos
Related Concept Videos
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and anaphylaxis:...
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Electroconvulsive Therapy

