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Updated: Aug 11, 2026

A Seminiferous Tubule Squash Technique for the Cytological Analysis of Spermatogenesis Using the Mouse Model
Published on: February 6, 2018
Meiotic studies and synaptonemal complex analysis in two infertile males with a 13/14 balanced translocation
Abstract:
Meiotic and synaptonemal complex studies by light and electron microscopy have been carried out in two infertile males with a balanced 13/14 translocation. As expected, all metaphase I figures in conventional meiotic preparations contained a chain trivalent. Synaptonemal complex studies showed typical trivalent images with incomplete pairing of the acrocentric elements in the cis configuration. A review of the literature shows that the fertility of these patients is quite variable. All of them show a slightly reduced number of chiasmata (mean 46.6). Pairing in cis, as detected by electron microscopic studies, does not seem to have a prognostic value.
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