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[Leg ulcers in essential thrombocythemia].

R Kaufmann, E Landes

    Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
    |May 1, 1984
    PubMed
    Summary
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    Essential thrombocythemia (ET) can uncommonly cause leg ulcers. This condition may also present with other skin issues, highlighting the importance of dermatological assessment in diagnosing ET.

    Area of Science:

    • Hematology
    • Dermatology
    • Internal Medicine

    Background:

    • Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by elevated platelet counts.
    • Cutaneous manifestations of ET are diverse but often underrecognized.
    • Leg ulcers are a rare but significant clinical presentation of ET.

    Observation:

    • Two case reports detail patients presenting with leg ulcers attributed to essential thrombocythemia.
    • The clinical course and diagnostic challenges in these cases are highlighted.
    • Associated cutaneous findings in ET are also briefly reviewed.

    Findings:

    • Essential thrombocythemia should be considered in the differential diagnosis of unexplained leg ulcers, particularly in the absence of other common causes.

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  • Prompt diagnosis and management of ET can prevent or treat associated ulcerative lesions.
  • This underscores the link between hematological disorders and dermatological conditions.
  • Implications:

    • Increased awareness among clinicians regarding the potential for ET to cause leg ulcers.
    • Improved diagnostic strategies for patients with refractory leg ulcers.
    • Further research into the pathogenesis of cutaneous manifestations in essential thrombocythemia.