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Updated: Sep 7, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
Published on: August 24, 2013
A comparison of in-vivo and imaginal participant modeling
Abstract:
Recent research indicates that effective treatments of phobic reactions are often performance-based and involve exposure to the phobic object. The present study was designed to determine whether both of these components were necessary for the effectiveness of participant modeling procedures (N = 26). Phobic individuals were assigned randomly to one of two forms of participant modeling: In-vivo vs. imaginal. Both treatment analogues were identical except that the in-vivo version involved actual exposure to a phobic object, while the imaginal version simply required individuals to imagine that the phobic object was physically present. Results on behavioral and self-report measures indicated that both in-vivo and imaginal participant modeling were effective in generating increased approach behavior, but neither produced generalization beyond the laboratory setting. Explanations were discussed.

