Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

234
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
234
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

1.1K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
1.1K
The Thyroid Gland01:23

The Thyroid Gland

7.8K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

5.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.7K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.0K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.0K
Dimensional Analysis03:40

Dimensional Analysis

65.2K
Dimensional analysis, also known as the factor label method, is a versatile approach for mathematical operations. The main principle behind this approach is: the units of quantities must be subjected to the same mathematical operations as their associated numbers. This method can be applied to computations ranging from simple unit conversions to more complex and multi-step calculations involving several different quantities and their units.
Conversion Factors and Dimensional Analysis
The unit...
65.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of glucose monitoring devices on relationships with food and eating behaviour for people with type 2 diabetes mellitus: A review of the literature.

Diabetes & metabolic syndrome·2026
Same author

Evaluating deuterated-xylene for use as a fusion neutron spectrometer.

The Review of scientific instruments·2024
Same author

Publisher's Note: "Ion optical design of the magnetic proton recoil neutron spectrometer for the SPARC tokamak" [Rev. Sci. Instrum. 95, 103502 (2024)].

The Review of scientific instruments·2024
Same author

Overview of the early campaign diagnostics for the SPARC tokamak (invited).

The Review of scientific instruments·2024
Same author

Overview of the neutron diagnostic systems for the SPARC tokamak.

The Review of scientific instruments·2024
Same author

Ion optical design of the magnetic proton recoil neutron spectrometer for the SPARC tokamak.

The Review of scientific instruments·2024

Related Experiment Video

Updated: Feb 13, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.5K

Thyroid replacement in thyroparathyroidectomized dogs.

H N Hulter, L E Gustafson, E L Bonner

    Mineral and Electrolyte Metabolism
    |January 1, 1984
    PubMed
    Summary

    Determining optimal thyroid hormone replacement in thyroparathyroidectomized dogs is crucial. Intravenous administration of 10 micrograms/kg daily sodium levothyroxine effectively normalized serum thyroxine (T4) levels post-surgery.

    Area of Science:

    • Veterinary Physiology
    • Endocrinology

    Background:

    • The thyroparathyroidectomized dog is a key model for studying hypoparathyroidism.
    • Established thyroid hormone replacement protocols are lacking for this model.

    Purpose of the Study:

    • To determine the appropriate thyroid hormone replacement dose for achieving euthyroidism in thyroparathyroidectomized dogs.

    Main Methods:

    • Dogs underwent thyroparathyroidectomy and received sodium levothyroxine replacement via subcutaneous, oral, or intravenous routes at varying doses.
    • Serum thyroxine (T4) concentrations were measured pre- and post-treatment.

    Main Results:

    • Subcutaneous T4 replacement (2.4 micrograms/kg daily) significantly decreased serum T4 levels.
    • Oral T4 replacement (20 micrograms/kg daily) did not significantly alter serum T4 levels.

    More Related Videos

    Spontaneous Murine Model of Anaplastic Thyroid Cancer
    05:39

    Spontaneous Murine Model of Anaplastic Thyroid Cancer

    Published on: February 3, 2023

    2.3K
    The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs
    08:59

    The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs

    Published on: October 13, 2017

    18.3K

    Related Experiment Videos

    Last Updated: Feb 13, 2026

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
    04:39

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

    Published on: March 17, 2023

    2.5K
    Spontaneous Murine Model of Anaplastic Thyroid Cancer
    05:39

    Spontaneous Murine Model of Anaplastic Thyroid Cancer

    Published on: February 3, 2023

    2.3K
    The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs
    08:59

    The Other End of the Leash: An Experimental Test to Analyze How Owners Interact with Their Pet Dogs

    Published on: October 13, 2017

    18.3K
  • Intravenous T4 replacement at 10 micrograms/kg daily normalized both total and free serum T4 concentrations.

    • Conclusions:

    • Intravenous sodium levothyroxine at 10 micrograms/kg daily is effective for normalizing serum T4 in thyroparathyroidectomized dogs.
    • Suboptimal doses via subcutaneous or intravenous routes result in decreased serum T4 levels.