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Progressive interstitial pulmonary lobar emphysema.

H Zimmermann

    European Journal of Pediatrics
    |May 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Progressive Pulmonary Interstitial Emphysema (PIPE) in premature infants is a serious complication of mechanical ventilation for Respiratory Distress Syndrome (RDS). This condition arises from alveolar air leaks into lymphatic vessels, necessitating prompt treatment.

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    Area of Science:

    • Neonatal Medicine
    • Pediatric Pulmonology
    • Respiratory Physiology

    Background:

    • Premature infants with Respiratory Distress Syndrome (RDS) often require artificial ventilation.
    • Artificial ventilation can lead to complications, including Progressive Pulmonary Interstitial Emphysema (PIPE).

    Observation:

    • Three cases of progressive PIPE in premature infants are presented.
    • The study observed air escaping through alveolar leaks into the pulmonary lymphatic capillary system.
    • This leakage caused dilation of lymphatic channels, characteristic of PIPE.

    Findings:

    • Progressive Pulmonary Interstitial Emphysema (PIPE) is caused by alveolar air leaks.
    • The escaped air enters the pulmonary lymphatic system, leading to lymphatic channel dilation.

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  • This process exerts a compressive effect on adjacent lung areas.

    • Implications:

    • PIPE requires rapid and effective therapeutic intervention due to its progressive nature.
    • Conservative management approaches are suggested for PIPE.
    • Lobectomy is contraindicated in cases of severe bronchopulmonary dysplasia resulting from prolonged ventilation with high oxygen concentrations.