[Long-term modifications in unequal size small intestine anastomoses in the rat]
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Updated: Sep 23, 2026

Orthotopic Small Bowel Transplantation in Rats
Published on: November 6, 2012
Abstract:
Long-term modifications in unequal size small intestine anastomoses were studied in a group of 20 rats, following operation during the neonatal period. Isolated small intestine loops in anisoperistalsis were then replaced in the abdomen during the growing period, the animals being sacrificed after reaching adults age. Various plastic procedures to correct the unequal size were studied, as well as the histological results both in the anastomoses themselves and the replaced isolated loops. Preliminary results tend to demonstrate that the only valid techniques were those plastic operations in which the dilated loops were remodelled, and that any dilated intestinal segment present during the neonatal period will remain dilated in spite of the permeable anastomosis.

