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Perineural invasion by squamous-cell carcinoma.
The Journal of Dermatologic Surgery and Oncology
|July 1, 1982
Summary
Perineural invasion by squamous-cell carcinoma is a serious indicator. However, a multidisciplinary approach, including Mohs' surgery, achieved successful outcomes in seventeen cases.
Area of Science:
- Oncology
- Dermatology
- Surgical Pathology
Background:
- Perineural invasion (PNI) in squamous-cell carcinoma (SCC) is historically associated with poor prognosis.
- Early detection and management of PNI are critical for improving patient outcomes.
Observation:
- This study reviewed seventeen cases of SCC with confirmed perineural invasion.
- The cases involved both pathologist and chemosurgeon identification of PNI.
Findings:
- A multidisciplinary treatment strategy, incorporating Mohs' surgery, led to successful outcomes in all seventeen cases of PNI.
- This approach effectively managed SCC with perineural spread.
Implications:
- Multidisciplinary care, including specialized surgical techniques like Mohs' surgery, can overcome the challenges posed by perineural invasion in SCC.
- These findings support the integration of comprehensive treatment plans for SCC patients with PNI.