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Giardiasis: nutritional implications.

N W Solomons

    Reviews of Infectious Diseases
    |July 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Giardiasis, an infection by Giardia lamblia, causes nutrient malabsorption and can affect growth. Research focuses on its prevalence and nutritional impact, especially in children.

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    Area of Science:

    • Gastroenterology
    • Infectious Diseases
    • Nutritional Science

    Background:

    • The pathogenicity of Giardia lamblia is established, shifting focus to infection prevalence and nutritional consequences.
    • Giardiasis can lead to steatorrhea, maldigestion, and malabsorption of carbohydrates and vitamins A and B12.
    • Mechanisms of absorptive dysfunction are unclear, possibly involving intestinal mucosal abnormalities or bacterial overgrowth.

    Purpose of the Study:

    • To investigate the nutritional impact of Giardia lamblia infections, including clinical and subclinical cases.
    • To explore factors predisposing to giardial infection, such as protein-energy malnutrition.
    • To highlight limitations in diagnosing giardiasis and its nutritional correlates.

    Main Methods:

    • Review of existing literature on Giardia lamblia pathogenicity and nutritional effects.

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  • Analysis of clinical manifestations including steatorrhea, maldigestion, and malabsorption.
  • Discussion of potential contributing factors like bacterial overgrowth and host nutritional status.

    • Main Results:

    • Giardiasis is associated with significant malabsorption and can cause failure to thrive in children.
    • Subclinical giardiasis's impact on general population growth remains undefined.
    • Protein-energy malnutrition may increase susceptibility to giardiasis.

    Conclusions:

    • Further research is needed to understand the full nutritional impact of both clinical and subclinical giardiasis.
    • Development of sensitive, noninvasive diagnostic tests is crucial for studying nutritional correlates.
    • Giardiasis poses a significant nutritional challenge, particularly in vulnerable populations.