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[Results of renal transplantation in childhood]

R Rauhs, O Wagner, G Kretschmer

    Zeitschrift Fur Kinderchirurgie : Organ Der Deutschen, Der Schweizerischen Und Der Osterreichischen Gesellschaft Fur Kinderchirurgie = Surgery in Infancy and Childhood
    |July 1, 1982
    PubMed

    Insights

    Kidney transplantation in children with chronic kidney disease offers optimal therapy. Most pediatric renal allografts function long-term, enabling full rehabilitation for young patients.

    Area of Science:

    • Pediatric Nephrology
    • Surgical Innovation
    • Transplantation Medicine

    Context:

    • Chronic renal insufficiency in childhood presents significant challenges.
    • Limited therapeutic options for end-stage renal disease in pediatric populations.
    • Advancements in surgical techniques and immunosuppression have improved allograft outcomes.

    Purpose:

    • To evaluate the long-term efficacy and outcomes of renal allografts in pediatric patients.
    • To assess the functional status and rehabilitation of children post-kidney transplantation.
    • To determine the optimal treatment strategy for chronic renal insufficiency in childhood.

    Summary:

    • 37 renal allografts were performed in 27 children aged 2-16 years.
    • 67% of allografts maintained function for over one year.
    • At the start of 1981, 13 children had functioning grafts with a median serum creatinine of 1.8 +/- 1.2 mg/dL; 4 had grafts functioning for over 7 years.
    • All children with functioning grafts achieved full rehabilitation.

    Impact:

    • Renal transplantation is identified as the optimal therapy for chronic renal insufficiency in children.
    • Successful transplantation leads to improved quality of life and full rehabilitation.
    • Demonstrates the viability and effectiveness of pediatric kidney transplantation for long-term patient well-being.

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