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Updated: Jul 21, 2026

The Trier Social Stress Test Protocol for Inducing Psychological Stress
Published on: October 19, 2011
Seasonal alteration in response to stress or physiological change
Abstract:
Two pilot experiments are reported in which various combinations of stress, modifiers of glucose metabolism, and sulfur deficiency were investigated using urinary sulfur levels and tissue glucose and glycogen levels as indicators. Urinary sulfur levels increased under certain conditions of stress but decreased with the injection of Escherichia coli endotoxin, suggesting an anabolic reversal. Heart and blood glycogen levels fell in rats fed a sulfur-deficient diet. These results are discussed in relation to seasonal variations in protein and glucose metabolism.
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