Comparison of fluorescent immunoassay and EMIT for assay of serum primidone concentration

A fluorescent immunoassay procedure (FIA) for the assay of serum of plasma primidone concentrations that was developed by Ames Laboratories is compared to the established enzyme-multiplied immunoassay technique (EMIT) developed by Syva. The FIA compares favorably with the established EMIT system for accuracy, and the FIA is eight times more sensitive but requires a greater turnover time.