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Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo Using Biodegradable Poly(lactic-co-glycolic acid) Microspheres
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[Effect of exogenous insulin on the proliferative activity of polypotent hematopoietic stem cells in mice]
Tsitologiia
|July 1, 1982
Abstract:
The effect of insulin on the process of endogenous and exogenous spleen colony-formation in mice of Swiss strain was studied. In mice that received insulin the endogenous colony-formation was depressed for a short time, this process being glucose dependent. The number of spleen exogenous CFU decreased when the donors of bone marrow received insulin. A modulate influence of the hormone on the stem cell cycle has been shown.

