[Autogenous heterotopic pancreas segment transplantation in the dog]

In 50 mongrel dogs autogenous heterotopic transplantation of pancreatic segments was performed without duct ligation. Analyses of the endocrine function of the transplant up to 275 days yielded reduced glucose tolerance and simultaneously normoglycaemia as well as stimulation of insulin release following administration of glucose and no early reflex insulin incretion following oral glucose administration. The exocrine pancreas tissue disappeared nearly completely and inside big complexes of isles mitoses could be observed. The A:B-cell relation had changed. The reduction of the transplanted tissue mass to one third was also evident by angiography.