[L-transforming effect of furazolidone on Shigella flexneri cells]

The capacity of furazolidone for L-transformation of Shigella flexneri was studied with its incubation on 1.3 per cent placenta serum salt Difco agar. It was found that a single exposure of Shigella cells to 0.05 microgram/ml of furazolidone resulted in transformation of some of them to the elements characteristic of the L-forms, i.e. spherical and granular forms capable of reproduction on routine nutrient media and possessing pronounced sensitivity to penicillin.