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[Possible participation of the ribosomes in the contractile function of microfilaments in morphogenetic processes]

V N Meshcheriakov, L E Zavalishina, L V Belousov

    Ontogenez
    |September 1, 1982
    PubMed

    Insights

    Early embryogenesis may involve polysomes binding myosin and interacting with actin microfilaments. This interaction could enhance cell contraction and transplantation rates, linking protein synthesis to morphogenesis.

    Area of Science:

    • Molecular Biology
    • Cell Biology
    • Developmental Biology

    Context:

    • Early embryogenesis involves complex cellular processes.
    • Actin microfilaments and myosin are key components of the cytoskeleton.
    • Protein synthesis rates correlate with morphogenetic events.

    Purpose:

    • To propose a novel mechanism for non-muscle contraction during early embryogenesis.
    • To investigate the potential role of polysomes in cytoskeletal regulation.
    • To link protein synthesis to cellular morphogenetic processes.

    Summary:

    • A hypothesis suggests that during early embryogenesis, polysomes bind to myosin.
    • This binding facilitates interaction with actin microfilaments, activating their contractile function.
    • This process may increase the rate of transplantation and is linked to actin depolymerization.

    Impact:

    • Provides a potential explanation for the correlation between high protein synthesis and rapid morphogenesis.
    • Offers a framework for predicting the effects of protein synthesis inhibitors on development.
    • Suggests new insights into the role of the cytoskeleton in embryonic development.

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