[Antineoplastic chemotherapy in advanced gastric cancer]
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Updated: Sep 19, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Abstract:
Antineoplastic agents are active in advanced gastric cancer. With great probability polychemotherapy is more effective than single-drug treatment. With respect to the definition of the optimal polychemotherapy regimen there is more speculation than scientific evidence. At present mostly combinations containing fluorouracil + doxorubicin as FAM or FAMe are recommended. With such regimens remission rates of 40% and a mean survival time of 5-6 months can be expected. In conclusion the results of antineoplastic chemotherapy in advanced gastric cancer are unsatisfactory. For the future are necessary, --intensive efforts synthesizing new compounds --further efforts concerning adequate investigations of all antineoplastic drugs active in solid tumours considering also new routes of administration (ftorafur oral) --qualified experimental and clinical research to elaborate active and well-defined polychemotherapy regimens basing on an adequate scientific background.
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